Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.69 |
| ▸ | PPARG | P37231 | 6/20 | 0.69 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947519 | 0.82 | EPHX2 (0.66) | EPHX2PPARGHTTROCK2ROCK1 | |
| SCHEMBL28647893 | 0.81 | PPARG (1.00) | EPHX2PPARGPPARDPPARA | |
| SCHEMBL28643158 | 0.81 | EPHX2 (0.66) | EPHX2PPARGPPARAHTTROCK2 | |
| SCHEMBL22987222 | 0.81 | EPHX2 (0.69) | EPHX2PPARGPPARDPPARAFFAR1 | |
| SCHEMBL28646196 | 0.80 | PPARG (0.60) | EPHX2PPARGNR1H4HTTROCK2 | |
| SCHEMBL1508357 | 0.78 | FFAR1 (0.56) | PPARGFFAR1RORCHDAC1RXRA | |
| SCHEMBL30055829 | 0.78 | FFAR1 (0.56) | PPARGFFAR1RORCHDAC1RXRA | |
| SCHEMBL22987232 | 0.78 | EPHX2 (0.67) | EPHX2PPARGPPARDPPARAFFAR1 | |
| SCHEMBL28654120 | 0.78 | SMN1; SMN2 (0.68) | EPHX2PPARGFFAR1NR1H4 | |
| SCHEMBL22987225 | 0.77 | PPARG (0.81) | EPHX2PPARGFFAR1NR1H4ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238125-A1 | Diabetes and Metabolic Syndrome Treatment with a Novel Dual Modulator of Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptors | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2021-08-05 | — | — | US | disclosed |
| US-10927069-B2 | Diabetes and metabolic syndrome treatment with a novel dual modulator of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | THE MEDICAL COLLEGE OF WISCONSIN, INC. (US) | 2021-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10927069-B2 | Diabetes and metabolic syndrome treatment with a novel dual modulator of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | EPHX1, EPHX2, PPARG | EPHX2 2/4885PPARG 3/4885PPARD 9/4885 |
| US-20210238125-A1 | Diabetes and Metabolic Syndrome Treatment with a Novel Dual Modulator of Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptors | EPHX1, EPHX2, PPARG | EPHX2 2/4885PPARG 3/4885PPARD 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.