Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B13 | Q7Z5P4 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13947519 | 0.85 | EPHX2 (0.66) | PPARGEPHX2ROCK2ROCK1HDAC1 | |
| SCHEMBL28648368 | 0.81 | EPHX2 (0.68) | PPARGEPHX2ALOX5 | |
| SCHEMBL22987233 | 0.80 | EPHX2 (0.69) | PPARGEPHX2ROCK2ROCK1HDAC1 | |
| SCHEMBL15338437 | 0.79 | HDAC3 (0.50) | PPARGEPHX2ROCK2ROCK1HDAC1 | |
| SCHEMBL13876187 | 0.78 | EPHX2 (0.58) | PPARGEPHX2ROCK2ROCK1HDAC1 | |
| SCHEMBL16761098 | 0.77 | EPHX2 (0.60) | EPHX2 | |
| SCHEMBL3710899 | 0.77 | EPHX2 (0.69) | PPARGEPHX2ROCK2ROCK1HDAC1 | |
| SCHEMBL28649243 | 0.77 | EPHX2 (0.70) | PPARGEPHX2ROCK2ROCK1NR1H4 | |
| SCHEMBL28348748 | 0.77 | EPHX2 (0.61) | PPARGEPHX2ROCK2ROCK1HDAC1 | |
| SCHEMBL29258115 | 0.76 | NAMPT (0.52) | PPARGEPHX2ROCK2ROCK1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026028-B | Treatment of diabetes and metabolic syndrome with novel dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors | 威斯康星州医药大学股份有限公司 | 2021-11-09 | — | — | CN | disclosed |