Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27072723 | 0.85 | CYP2D6 (0.39) | CYP2D6CTSSCTSKCA1CA2 | |
| SCHEMBL18924130 | 0.85 | CYP2D6 (0.39) | CYP2D6CTSSCTSKCA1CA2 | |
| SCHEMBL30143407 | 0.85 | TERT (0.44) | CYP2D6CTSSCTSKDPP4DPP8 | |
| SCHEMBL27701223 | 0.84 | DPP4 (0.37) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL19319010 | 0.83 | TET2 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL9805212 | 0.83 | TET2 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL16668048 | 0.83 | TET2 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL12884403 | 0.81 | CYP2D6 (0.42) | CYP2D6CTSSCTSKCA1CA2 | |
| SCHEMBL12017898 | 0.81 | CYP2D6 (0.41) | CYP2D6CTSSCTSKCA1CA2 | |
| SCHEMBL21141296 | 0.80 | DPP4 (0.39) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778601-A1 | CYTOTOXIC BENZODIAZEPINE DERIVATIVES | ImmunoGen, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |