Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 14/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987792 | 0.81 | HSP90AB1 (0.43) | ADORA2AADORA3ADORA1HSP90AB1ADORA2B | |
| SCHEMBL22987589 | 0.79 | ADORA3 (0.46) | ADORA2AADORA3ADORA1KDM4EBRD4 | |
| SCHEMBL22987552 | 0.78 | KDM4E (0.51) | ADORA2AADORA3ADORA1HSP90AB1KDM4E | |
| SCHEMBL29646116 | 0.76 | ADORA2A (0.38) | ADORA2AADORA3ADORA1HSP90AB1BRD4 | |
| SCHEMBL22987759 | 0.76 | KDM4E (0.47) | ADORA3KDM4EBRD4 | |
| SCHEMBL22988089 | 0.76 | HSP90AB1 (0.41) | ADORA2AHSP90AB1KDM4EADORA2B | |
| SCHEMBL22988090 | 0.74 | HSP90AB1 (0.45) | ADORA2AADORA3ADORA1HSP90AB1KDM4E | |
| SCHEMBL22987794 | 0.74 | KDM4E (0.43) | ADORA2AADORA3ADORA1HSP90AB1KDM4E | |
| SCHEMBL22987764 | 0.73 | ADORA2A (0.41) | ADORA2AHSP90AB1BRD4ADORA2B | |
| SCHEMBL22988018 | 0.72 | ADORA2A (0.42) | ADORA2AHSP90AB1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | ADORA2A 103/4885ADORA3 34/4885ADORA1 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.