Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | ADA | P00813 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22988327 | 0.87 | ADORA1 (0.47) | ADORA3ADORA1ADORA2AACP1MAPT | |
| SCHEMBL22979755 | 0.86 | ADORA3 (0.50) | ADORA3ADORA1ADORA2AACP1MAPT | |
| SCHEMBL29646450 | 0.86 | ADORA3 (0.50) | ADORA3ADORA1ADORA2AACP1MAPT | |
| SCHEMBL22988304 | 0.84 | ADORA3 (0.65) | ADORA3ADORA1ADORA2AMAPTTHRB | |
| SCHEMBL22987511 | 0.82 | ADORA3 (0.45) | ADORA3ADORA1ADORA2AMAPTADA | |
| SCHEMBL31150001 | 0.80 | ADORA3 (0.41) | ADORA3ADORA1ADORA2AACP1MAPT | |
| SCHEMBL22988235 | 0.78 | ADORA3 (0.51) | ADORA3ADORA1ADORA2AMAPT | |
| SCHEMBL30393303 | 0.77 | NPC1 (0.52) | ADORA3ADORA1ADORA2AACP1MAPT | |
| SCHEMBL22988309 | 0.77 | ADORA3 (0.53) | ADORA3ADORA1ADORA2AMAPT | |
| SCHEMBL22988361 | 0.76 | PDE10A (0.53) | ADORA3ADORA1ADORA2AMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |