Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645447 | 1.00 | CCNT1 (0.36) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22980984 | 1.00 | CCNT1 (0.36) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL29645785 | 1.00 | CCNT1 (0.36) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22988096 | 0.98 | CCNK (0.38) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL29645772 | 0.98 | CCNK (0.38) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22988029 | 0.94 | CCNT1 (0.36) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL29645816 | 0.94 | CCNT1 (0.36) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22979395 | 0.92 | HDAC1 (0.35) | ADORA2AADORA1ADORA3ADORA2BPTK2 | |
| SCHEMBL22988088 | 0.92 | ADORA2A (0.35) | ADORA2AADORA1ADORA3ADORA2BBRD4 | |
| SCHEMBL22988167 | 0.92 | CCNE1 (0.36) | ADORA2AADORA1ADORA3ADORA2BPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | CCNT1 927/4885CCNK 1143/4885CDK7 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.