Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CCNH | P51946 | 1/20 | 0.36 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.36 |
| ▸ | BRD4 | O60885 | 4/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645447 | 1.00 | CCNT1 (0.36) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22980984 | 1.00 | CCNT1 (0.36) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22987956 | 1.00 | CCNT1 (0.36) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22988096 | 0.98 | CCNK (0.38) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL29645772 | 0.98 | CCNK (0.38) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22988029 | 0.94 | CCNT1 (0.36) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL29645816 | 0.94 | CCNT1 (0.36) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22979395 | 0.92 | HDAC1 (0.35) | ADORA2AADORA1ADORA3ADORA2BPTK2 | |
| SCHEMBL22988088 | 0.92 | ADORA2A (0.35) | ADORA2AADORA1ADORA3ADORA2BBRD4 | |
| SCHEMBL22988167 | 0.92 | CCNE1 (0.36) | ADORA2AADORA1ADORA3ADORA2BPTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466850-B | [1,2,4] Triazolo [1,5-C ] quinazolin-5-amine | 拜耳股份有限公司 | 2024-09-10 | — | — | CN | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |