Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 3/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.38 |
| ▸ | CDK7 | P50613 | 2/20 | 0.38 |
| ▸ | CCNH | P51946 | 2/20 | 0.38 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.34 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.34 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.34 |
| ▸ | RPS17 | P08708 | 1/20 | 0.34 |
| ▸ | RPSA | P08865 | 1/20 | 0.34 |
| ▸ | RPS2 | P15880 | 1/20 | 0.34 |
| ▸ | RPL35A | P18077 | 1/20 | 0.34 |
| ▸ | RPL7 | P18124 | 1/20 | 0.34 |
| ▸ | RPL17 | P18621 | 1/20 | 0.34 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.34 |
| ▸ | RPS3 | P23396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29645793 | 1.00 | CCNK (0.38) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL22979180 | 0.92 | MAP4K3 (0.32) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL29645522 | 0.92 | PDE3B (0.33) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL29645628 | 0.92 | MAP4K3 (0.32) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL22988441 | 0.92 | PDE3B (0.33) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL22979392 | 0.92 | PDE3B (0.33) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL22979833 | 0.92 | MAP4K3 (0.32) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL22988029 | 0.91 | CCNT1 (0.36) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL29645816 | 0.91 | CCNT1 (0.36) | CCNKCDK12CDK7CCNHMNAT1 | |
| SCHEMBL22988129 | 0.91 | PIM1 (0.33) | CCNKCDK12CDK7CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
| WO-2021028382-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | CCNK 1143/4885CDK12 1975/4885CDK7 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.