Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.32 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.32 |
| ▸ | CYP3A43 | Q9HB55 | 2/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | KHK | P50053 | 5/20 | 0.32 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22979833 | 1.00 | MAP4K3 (0.32) | MAP4K3CCNT1CCNKCDK7CDK9 | |
| SCHEMBL22979180 | 1.00 | MAP4K3 (0.32) | MAP4K3CCNT1CCNKCDK7CDK9 | |
| SCHEMBL22988396 | 0.92 | CCNK (0.38) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL29645793 | 0.92 | CCNK (0.38) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22979395 | 0.90 | HDAC1 (0.35) | TLR8CYP1A2CYP3A4CYP3A5CYP3A7 | |
| SCHEMBL22988441 | 0.90 | PDE3B (0.33) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL29645522 | 0.90 | PDE3B (0.33) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22979392 | 0.90 | PDE3B (0.33) | CCNT1CCNKCDK7CDK9CCNH | |
| SCHEMBL22988292 | 0.89 | CYP1A2 (0.33) | MAP4K3CYP1A2CYP3A4CYP3A5CYP3A7 | |
| SCHEMBL22988293 | 0.89 | CYP1A2 (0.33) | MAP4K3CYP1A2CYP3A4CYP3A5CYP3A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013508-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | Bayer Aktiengesellschaft (DE) | 2022-06-22 | — | — | EP | claimed |
| CN-114466850-A | [1,2,4] triazolo [1,5-C ] quinazolin-5-amines | 拜耳股份有限公司 | 2022-05-10 | — | — | CN | claimed |