SCHEMBL22988905

SCHEMBL22988905

c1ccc(-c2nc(-c3ccc4cc(-n5c6ccc7cccc8oc9cccc%10ccc5c(c%109)c6c78)ccc4c3)nc(-c3cccc4oc5ccccc5c34)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TERT O14746 2/20 0.33
ALDH1A1 P00352 3/20 0.33
HSD17B10 Q99714 3/20 0.33
KDM4E B2RXH2 2/20 0.33
TP53 P04637 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
CYP1A2 P05177 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MAPT P10636 2/20 0.32
TSHR P16473 2/20 0.32
MAPK1 P28482 2/20 0.32
HPGD P15428 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SIRT2 Q8IXJ6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22988907 0.94 S1PR1 (0.32) TERTALDH1A1HSD17B10KDM4ETP53
SCHEMBL22989251 0.93 S1PR5 (0.31) TERTSIRT2SIRT1
SCHEMBL22988913 0.91 KDM4E (0.32) TERTALDH1A1HSD17B10KDM4ETP53
SCHEMBL22988904 0.90 MEN1 (0.39) TERTALDH1A1HSD17B10KDM4ETP53
SCHEMBL22988953 0.90 CYP1A1 (0.34) TERTALDH1A1KDM4ESMN1; SMN2CYP1A2
SCHEMBL22988910 0.89 ALDH1A1 (0.41) ALDH1A1HSD17B10KDM4ETP53SMN1; SMN2
SCHEMBL22988911 0.89 S1PR5 (0.33)
SCHEMBL21862816 0.88 ABCG2 (0.34) TERTALDH1A1HSD17B10KDM4ETP53
SCHEMBL24118957 0.88 ALDH1A1 (0.34) ALDH1A1HSD17B10KDM4ETP53SMN1; SMN2
SCHEMBL23740552 0.87 ALDH1A1 (0.33) ALDH1A1HSD17B10KDM4ETP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed
US-20160340361-A1 PIPERIDINE INHIBITORS OF JANUS KINASE 3 AUSPEX PHARMACEUTICALS, INC. 2016-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160340361-A1 PIPERIDINE INHIBITORS OF JANUS KINASE 3 JAK2, JAK3, PAK3 TERT 1889/4885ALDH1A1 1603/4885HSD17B10 3604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.