SCHEMBL22988948

SCHEMBL22988948

c1ccc(-n2c3ccccc3c3ccc(-c4nc5ccccc5nc4-n4c5ccc6cccc7sc8cccc9ccc4c(c98)c5c67)cc32)cc1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GSR P00390 1/20 0.31
MEN1 O00255 1/20 0.30
HSP90AA1 P07900 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
PDE1B Q01064 1/20 0.30
PDE3A Q14432 1/20 0.30
PDE11A Q9HCR9 1/20 0.30
ALDH1A1 P00352 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22988951 0.95 KDM4E (0.35) KDM4EATML3MBTL1GSRPDE1B
SCHEMBL23031027 0.94 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL24245807 0.90 L3MBTL1 (0.41) KDM4EATML3MBTL1GSRMEN1
SCHEMBL23031022 0.89 KDM4E (0.32) KDM4EATML3MBTL1
SCHEMBL24245686 0.88 KDM4E (0.36) KDM4EATML3MBTL1GSRMEN1
SCHEMBL22989047 0.87 L3MBTL1 (0.35) KDM4EATML3MBTL1ALDH1A1RXFP1
SCHEMBL21366854 0.87 L3MBTL1 (0.35) KDM4EATML3MBTL1ALDH1A1RXFP1
SCHEMBL24245536 0.87 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1RXFP1
SCHEMBL18623571 0.87 KDM4E (0.40) KDM4EATML3MBTL1GSRMEN1
SCHEMBL24839414 0.86 KDM4E (0.35) KDM4EATML3MBTL1ALDH1A1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed
US-20160340361-A1 PIPERIDINE INHIBITORS OF JANUS KINASE 3 AUSPEX PHARMACEUTICALS, INC. 2016-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160340361-A1 PIPERIDINE INHIBITORS OF JANUS KINASE 3 JAK2, JAK3, PAK3 KDM4E 568/4885ATM 1893/4885L3MBTL1 4459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.