SCHEMBL22989028

SCHEMBL22989028

c1ccc2c(c1)oc1cc(-c3nc(-c4ccc(-n5c6ccc7cccc8oc9cccc%10ccc5c(c%109)c6c78)c5ccccc45)nc4c3oc3ccccc34)ccc12

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 1/20 0.35
TSHR P16473 3/20 0.32
TERT O14746 2/20 0.32
MAPT P10636 5/20 0.31
LMNA P02545 2/20 0.31
POLB P06746 2/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
KDM4E B2RXH2 2/20 0.30
ALOX5 P09917 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30
ALDH1A1 P00352 2/20 0.30
HPGD P15428 1/20 0.30
NPC1 O15118 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22989071 0.93 PRKDC (0.32) PRKDC
SCHEMBL22989018 0.91 TSHR (0.36) TSHRTERTMAPTLMNAPOLB
SCHEMBL22989014 0.91 TSHR (0.37) TSHRTERTMAPTLMNAPOLB
SCHEMBL22989238 0.91 TSHR (0.38) TSHRTERTMAPTLMNAPOLB
SCHEMBL22989023 0.90 PRKDC (0.31) PRKDC
SCHEMBL22989011 0.89 TSHR (0.31) TSHRMAPTLMNAPOLBHTT
SCHEMBL22989019 0.89 ALOX5 (0.34) PRKDCTSHRMAPTLMNAPOLB
SCHEMBL22988914 0.88 PRKDC (0.33) PRKDCTERTMAPTKMT2AKDM4E
SCHEMBL22989155 0.88 MEN1 (0.32) PRKDCKMT2A
SCHEMBL22988982 0.87 TSHR (0.38) TSHRTERTMAPTLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed
US-20160340361-A1 PIPERIDINE INHIBITORS OF JANUS KINASE 3 AUSPEX PHARMACEUTICALS, INC. 2016-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160340361-A1 PIPERIDINE INHIBITORS OF JANUS KINASE 3 JAK2, JAK3, PAK3 PRKDC 8/4885TSHR 3548/4885TERT 1889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.