SCHEMBL22989141

SCHEMBL22989141

c1ccc(-c2nc(-c3ccc(-n4c5ccc6cccc7oc8cccc9ccc4c(c98)c5c67)cc3)nc3ccccc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
ATM Q13315 1/20 0.48
WHR1 P49842 1/20 0.40
PDE5A O76074 1/20 0.36
ADORA2A P29274 1/20 0.35
NUDT1 P36639 1/20 0.35
ABCG2 Q9UNQ0 3/20 0.35
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MAPK1 P28482 2/20 0.35
HSD17B10 Q99714 2/20 0.35
TSHR P16473 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
CYP1A2 P05177 2/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2C9 P11712 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22989029 0.93 ATM (0.43) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL22989030 0.92 MEN1 (0.42) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL22989017 0.92 ATM (0.42) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL22989016 0.88 ATM (0.38) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL16284601 0.87 MEN1 (0.53) MEN1KMT2AATMWHR1PDE5A
SCHEMBL22988958 0.87 L3MBTL1 (0.34) MEN1KMT2AADORA2AABCG2ALDH1A1
SCHEMBL22989036 0.87 MEN1 (0.37) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL22989140 0.86 MEN1 (0.38) MEN1KMT2AATMWHR1ADORA2A
SCHEMBL22988966 0.86 TSHR (0.43) MEN1KMT2AALDH1A1KDM4EMAPT
SCHEMBL17286877 0.86 MEN1 (0.55) MEN1KMT2AATMWHR1PDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029757-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-02-18 WO disclosed