Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22978460 | 0.89 | CSF1R (0.60) | CSF1RCYP3A4CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL22989191 | 0.87 | CSF1R (0.49) | CSF1RCYP3A4CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL22989185 | 0.84 | CSF1R (0.48) | CSF1RCYP3A4CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL14705849 | 0.80 | NTRK1 (0.49) | CSF1RCYP3A4TLR7 | |
| SCHEMBL15102137 | 0.77 | CYP3A4 (0.63) | CSF1RCYP3A4CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL29883593 | 0.77 | CYP3A4 (0.63) | CSF1RCYP3A4CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL22989186 | 0.77 | CYP3A4 (0.43) | CSF1RCYP3A4CYP2C19CYP2C9FGFR1 | |
| SCHEMBL22988845 | 0.76 | CSF1R (0.49) | CSF1RCYP3A4CYP2C19CYP2C9TLR7 | |
| SCHEMBL21873075 | 0.76 | CYP1A2 (0.46) | CSF1RCYP3A4CYP2C19CYP2C9CYP1A2 | |
| SCHEMBL22988837 | 0.73 | MET (0.41) | CSF1RCYP3A4CYP2C19CYP2C9FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018233526-A9 | CSF1R INHIBITOR, AND MANUFACTURING METHOD THEREFOR AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2021-02-18 | — | — | WO | disclosed |