Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.71 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.71 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.62 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.62 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.62 |
| ▸ | GABRP | O00591 | 4/20 | 0.58 |
| ▸ | GABRD | O14764 | 4/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.58 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.58 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.58 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.58 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.58 |
| ▸ | GABRE | P78334 | 4/20 | 0.58 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.58 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.58 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12028989 | 1.00 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22989665 | 1.00 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL13701320 | 1.00 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL12028991 | 1.00 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL12028998 | 1.00 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL12028987 | 1.00 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22989702 | 0.94 | GRIN1 (0.67) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22989663 | 0.90 | GRIN1 (0.64) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22989902 | 0.90 | GRIN1 (0.64) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL18346701 | 0.89 | GRIN1 (0.68) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174569-A1 | PROCESS PER PREPARING (3a,5a)-20-OXOPREGNAN-3-YL GLYCYL-L-VALINATE HYDROCHLORIDE | INDUSTRIALE CHIMICA S.R.L. (IT) | 2023-06-08 | — | — | US | disclosed |
| US-20230174569-A1 | PROCESS PER PREPARING (3a,5a)-20-OXOPREGNAN-3-YL GLYCYL-L-VALINATE HYDROCHLORIDE | INDUSTRIALE CHIMICA S.R.L. (IT) | 2023-06-08 | — | — | US | disclosed |
| WO-2021027744-A1 | 3-HYDROXY-5-PREGNANE-20-ONE DERIVATIVE AND USE THEREOF | 南京诺瑞特医药科技有限公司 | 2021-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174569-A1 | PROCESS PER PREPARING (3a,5a)-20-OXOPREGNAN-3-YL GLYCYL-L-VALINATE HYDROCHLORIDE | CYP3A5, CYP17A1, UGT1A3 | GRIN1 50/4885GRIN2B 207/4885GRIN2D 179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.