Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.64 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.64 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.56 |
| ▸ | G6PD | P11413 | 6/20 | 0.52 |
| ▸ | GABRP | O00591 | 2/20 | 0.52 |
| ▸ | GABRD | O14764 | 2/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRE | P78334 | 2/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22989663 | 1.00 | GRIN1 (0.64) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22989988 | 0.93 | GRIN1 (0.66) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22990072 | 0.92 | GRIN1 (0.63) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22989835 | 0.92 | GRIN1 (0.63) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22989909 | 0.91 | GRIN1 (0.62) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22989687 | 0.90 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL22989665 | 0.90 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL12028989 | 0.90 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL12028987 | 0.90 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C | |
| SCHEMBL13701320 | 0.90 | GRIN1 (0.71) | GRIN1GRIN2BGRIN2DGRIN2AGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027744-A1 | 3-HYDROXY-5-PREGNANE-20-ONE DERIVATIVE AND USE THEREOF | 南京诺瑞特医药科技有限公司 | 2021-02-18 | — | — | WO | disclosed |