Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.46 |
| ▸ | FHIT | P49789 | 2/20 | 0.41 |
| ▸ | DTYMK | P23919 | 2/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22990460 | 1.00 | STING1 (0.46) | STING1FHITDTYMKP2RY1P2RY2 | |
| SCHEMBL22990428 | 0.91 | STING1 (0.42) | STING1FHITDTYMKP2RY1P2RY2 | |
| SCHEMBL22990422 | 0.88 | RNASEL (0.43) | DTYMKP2RY1P2RY2SRCSMN1; SMN2 | |
| SCHEMBL22872953 | 0.84 | RNASEL (0.49) | FHITADORA1 | |
| SCHEMBL22083402 | 0.84 | STING1 (0.49) | STING1NT5E | |
| SCHEMBL20324741 | 0.84 | STING1 (0.49) | STING1NT5E | |
| SCHEMBL20324531 | 0.84 | STING1 (0.49) | STING1NT5E | |
| SCHEMBL20225028 | 0.84 | RNASEL (0.51) | NT5EP2RX3 | |
| SCHEMBL22990429 | 0.81 | DTYMK (0.49) | STING1DTYMKP2RY1P2RY2SRC | |
| SCHEMBL22524006 | 0.81 | P2RY1 (0.56) | P2RY1P2RY2SRCSMN1; SMN2DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512861-B1 | CYCLIC DINUCLEOTIDES AS STING (STIMULATOR OF INTERFERON GENES) AGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-02-17 | — | — | EP | disclosed |