Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 5/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426097 | 0.83 | CCNB2 (0.42) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL30504220 | 0.81 | CCNB2 (0.39) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL22571176 | 0.80 | CCNB2 (0.46) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL2718523 | 0.80 | CDK1 (0.59) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL22571188 | 0.79 | CCNB2 (0.44) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL20052944 | 0.77 | AHCY (0.43) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL9702446 | 0.77 | CYP1A2 (0.51) | CDK1HTTADORA1ADORA3ADORA2A | |
| SCHEMBL26230985 | 0.76 | CCNB2 (0.45) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL24722333 | 0.76 | CCNB2 (0.41) | CDK1CCNB1CCNB2CCNB3CDK2 | |
| SCHEMBL20052009 | 0.76 | CCNB2 (0.44) | CDK1CCNB1CCNB2CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512861-B1 | CYCLIC DINUCLEOTIDES AS STING (STIMULATOR OF INTERFERON GENES) AGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-02-17 | — | — | EP | disclosed |