SCHEMBL22992137

SCHEMBL22992137

Clc1nc(-c2ccc3ccccc3c2)nc(-c2ccc3c(c2)oc2cc4ccccc4cc23)n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.38
AHR P35869 2/20 0.38
CYP1A2 P05177 4/20 0.37
SMN1; SMN2 Q16637 4/20 0.37
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 3/20 0.37
TP53 P04637 3/20 0.37
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
TSHR P16473 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36
CYP1A1 P04798 1/20 0.36
CYP1B1 Q16678 1/20 0.36
CYP11B1 P15538 2/20 0.35
CYP11B2 P19099 2/20 0.35
MAPT P10636 2/20 0.33
GSTP1 P09211 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24431771 0.93 AHR (0.41) NOTUMAHRCYP1A2SMN1; SMN2ALDH1A1
SCHEMBL23283905 0.92 AHR (0.46) NOTUMAHRCYP1A2SMN1; SMN2ALDH1A1
SCHEMBL30512300 0.91 AHR (0.49) NOTUMAHRCYP1A2SMN1; SMN2ALDH1A1
SCHEMBL20894572 0.91 AHR (0.49) NOTUMAHRCYP1A2SMN1; SMN2ALDH1A1
SCHEMBL23283871 0.91 AHR (0.38) NOTUMAHRCYP1A2SMN1; SMN2ALDH1A1
SCHEMBL23225905 0.91 AHR (0.38) AHRCYP1A2SMN1; SMN2ALDH1A1HSD17B10
SCHEMBL21239305 0.88 ALDH1A1 (0.42) NOTUMAHRCYP1A2SMN1; SMN2ALDH1A1
SCHEMBL23283840 0.88 CYP1A2 (0.38) NOTUMAHRCYP1A2SMN1; SMN2ALDH1A1
SCHEMBL23283771 0.87 AHR (0.42) NOTUMAHRCYP1A2SMN1; SMN2ALDH1A1
SCHEMBL22138511 0.87 SMN1; SMN2 (0.48) NOTUMCYP1A2SMN1; SMN2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029598-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-02-18 WO disclosed