Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 2/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29737271 | 0.84 | MAOA (0.52) | KMT2AMEN1USP2MAOAMAOB | |
| SCHEMBL1077580 | 0.84 | MAOA (0.52) | KMT2AMEN1USP2MAOAMAOB | |
| SCHEMBL10690124 | 0.77 | KMT2A (0.45) | KMT2AMEN1USP2MAOAMAOB | |
| SCHEMBL17875264 | 0.77 | KMT2A (0.45) | KMT2AMEN1USP2MAOAMAOB | |
| SCHEMBL10837410 | 0.77 | KMT2A (0.45) | KMT2AMEN1USP2MAOAMAOB | |
| SCHEMBL19561697 | 0.76 | KMT2A (0.40) | KMT2AMEN1USP2MAOAMAOB | |
| SCHEMBL11058577 | 0.75 | KMT2A (0.38) | KMT2AMEN1USP2MAOAMAOB | |
| SCHEMBL19954827 | 0.75 | KMT2A (0.37) | KMT2AMEN1USP2MAOAMAOB | |
| SCHEMBL22992504 | 0.75 | POLB (0.52) | KMT2AMEN1USP2L3MBTL1TSHR | |
| SCHEMBL22992502 | 0.75 | POLB (0.52) | KMT2AMEN1USP2L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027721-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2021-02-18 | — | — | WO | disclosed |