SCHEMBL22993103

SCHEMBL22993103

Fc1ccc(-c2c3ccccc3c(-c3ccc4ccccc4c3)c3ccc(-c4cccc(C(F)(F)F)c4)cc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
NR3C1 P04150 1/20 0.48
CYP1A1 P04798 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP1B1 Q16678 1/20 0.43
ESR1 P03372 2/20 0.43
TP53 P04637 1/20 0.39
ABCG2 Q9UNQ0 3/20 0.39
PDPK1 O15530 1/20 0.37
ENPP1 P22413 1/20 0.37
HSD17B1 P14061 1/20 0.37
HSD17B2 P37059 1/20 0.37
MAPK14 Q16539 1/20 0.37
MAOB P27338 1/20 0.36
CNR2 P34972 1/20 0.36
NPY5R Q15761 1/20 0.36
PLG P00747 1/20 0.36
PLAU P00749 1/20 0.36
PLAT P00750 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22992956 0.94 CYP1A1 (0.47) PGRTDP1NR3C1CYP1A1CYP1A2
SCHEMBL22993104 0.92 ESR1 (0.47) PGRTDP1NR3C1CYP1A1CYP1A2
SCHEMBL22993296 0.91 CYP1A1 (0.45) PGRTDP1NR3C1CYP1A1CYP1A2
SCHEMBL22993057 0.90 CYP1A1 (0.44) PGRTDP1NR3C1CYP1A1CYP1A2
SCHEMBL22993369 0.90 TDP1 (0.44) PGRTDP1NR3C1CYP1A1CYP1A2
SCHEMBL22993056 0.89 PTPN5 (0.43) PGRTDP1NR3C1CYP1A1CYP1A2
SCHEMBL21223724 0.88 CYP1A2 (0.48) PGRTDP1NR3C1CYP1A1CYP1A2
SCHEMBL22993513 0.88 ESR1 (0.44) PGRTDP1NR3C1CYP1A1CYP1A2
SCHEMBL13828213 0.88 ESR1 (0.44) PGRTDP1NR3C1CYP1A1CYP1A2
SCHEMBL13827986 0.88 ESR1 (0.44) PGRTDP1NR3C1CYP1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed