SCHEMBL22993104

SCHEMBL22993104

FC(F)(F)c1ccc(-c2c3ccccc3c(-c3ccc4ccccc4c3)c3ccc(-c4cccc(C(F)(F)F)c4)cc23)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.47
CYP1A1 P04798 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP1B1 Q16678 1/20 0.44
PGR P06401 2/20 0.44
TDP1 Q9NUW8 1/20 0.42
EPHX2 P34913 1/20 0.41
KIF11 P52732 2/20 0.40
NR3C1 P04150 1/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
PDPK1 O15530 1/20 0.38
MAPK14 Q16539 1/20 0.38
MAOB P27338 1/20 0.38
CNR2 P34972 1/20 0.38
ABCG2 Q9UNQ0 1/20 0.38
PLG P00747 1/20 0.37
PLAU P00749 1/20 0.37
PLAT P00750 1/20 0.37
KDM1A O60341 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993057 0.97 CYP1A1 (0.44) ESR1CYP1A1CYP1A2CYP1B1PGR
SCHEMBL22992956 0.96 CYP1A1 (0.47) ESR1CYP1A1CYP1A2CYP1B1PGR
SCHEMBL22993296 0.93 CYP1A1 (0.45) ESR1CYP1A1CYP1A2CYP1B1PGR
SCHEMBL22993513 0.93 ESR1 (0.44) ESR1CYP1A1CYP1A2CYP1B1PGR
SCHEMBL22993103 0.92 PGR (0.48) ESR1CYP1A1CYP1A2CYP1B1PGR
SCHEMBL22993062 0.92 KIF11 (0.50) ESR1CYP1A2KIF11HSD17B1HSD17B2
SCHEMBL22993522 0.92 ESR1 (0.45) ESR1CYP1A1CYP1A2CYP1B1KIF11
SCHEMBL22993056 0.91 PTPN5 (0.43) ESR1CYP1A1CYP1A2CYP1B1PGR
SCHEMBL22978401 0.90 KIF11 (0.46) ESR1CYP1A1CYP1A2CYP1B1KIF11
SCHEMBL21223724 0.90 CYP1A2 (0.48) ESR1CYP1A1CYP1A2CYP1B1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed