SCHEMBL22993208

SCHEMBL22993208

CC(C)(C)c1ccc(-c2c3ccccc3c(-c3ccc4ccccc4c3)c3ccc(-c4ccc(OC(F)(F)F)cc4)cc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 3/20 0.43
TRPV1 Q8NER1 2/20 0.41
ACP1 P24666 1/20 0.39
EPHX2 P34913 1/20 0.38
NR1H4 Q96RI1 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
KIF11 P52732 1/20 0.36
SCN5A Q14524 1/20 0.35
GPR84 Q9NQS5 1/20 0.34
MMP3 P08254 1/20 0.34
P2RY1 P47900 1/20 0.34
ESR1 P03372 2/20 0.33
AURKA O14965 1/20 0.33
TPX2 Q9ULW0 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993533 0.92 ACP1 (0.41) SERPINE1ACP1KIF11SCN5AMMP3
SCHEMBL22993519 0.91 ESR1 (0.39) SERPINE1TRPV1ACP1KIF11SCN5A
SCHEMBL22993279 0.90 ACP1 (0.42) SERPINE1ACP1KIF11SCN5AMMP3
SCHEMBL22993064 0.89 ACP1 (0.43) SERPINE1ACP1KIF11SCN5AMMP3
SCHEMBL22992902 0.88 ACP1 (0.40) SERPINE1ACP1KIF11SCN5AMMP3
SCHEMBL22993100 0.88 ACP1 (0.40) SERPINE1ACP1KIF11SCN5AMMP3
SCHEMBL21235654 0.88 ESR1 (0.41) TRPV1ACP1KIF11GPR84ESR1
SCHEMBL22993246 0.88 SERPINE1 (0.39) SERPINE1TRPV1ACP1EPHX2NR1H4
SCHEMBL22993382 0.88 PPARG (0.42) SERPINE1TRPV1ACP1EPHX2NR1H4
SCHEMBL22993077 0.88 SERPINE1 (0.39) SERPINE1TRPV1ACP1EPHX2NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed