SCHEMBL22993246

SCHEMBL22993246

CC(C)(C)c1ccc(-c2c3ccccc3c(-c3cc4ccccc4c4ccccc34)c3ccc(-c4ccc(OC(F)(F)F)cc4)cc23)cc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.39
TRPV1 Q8NER1 2/20 0.39
GPR84 Q9NQS5 1/20 0.39
ACP1 P24666 1/20 0.37
PPARG P37231 2/20 0.36
PPARA Q07869 2/20 0.36
EPHX2 P34913 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
CYP11B1 P15538 3/20 0.35
CYP11B2 P19099 3/20 0.35
KIF11 P52732 1/20 0.34
SCN5A Q14524 1/20 0.33
P2RY1 P47900 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993077 1.00 SERPINE1 (0.39) SERPINE1TRPV1GPR84ACP1PPARG
SCHEMBL22993516 0.98 TRPV1 (0.41) SERPINE1TRPV1GPR84ACP1PPARG
SCHEMBL22993294 0.92 SERPINE1 (0.37) SERPINE1TRPV1GPR84ACP1PPARG
SCHEMBL22993151 0.91 CYP11B1 (0.36) SERPINE1TRPV1ACP1CYP11B1CYP11B2
SCHEMBL22993300 0.91 CYP11B1 (0.36) SERPINE1TRPV1ACP1CYP11B1CYP11B2
SCHEMBL22993072 0.90 ACP1 (0.41) SERPINE1ACP1CYP11B1CYP11B2KIF11
SCHEMBL22992970 0.90 ACP1 (0.41) SERPINE1ACP1CYP11B1CYP11B2KIF11
SCHEMBL22993382 0.89 PPARG (0.42) SERPINE1TRPV1GPR84ACP1PPARG
SCHEMBL22993254 0.89 ACP1 (0.38) SERPINE1GPR84ACP1CYP11B1CYP11B2
SCHEMBL22993518 0.89 CYP11B1 (0.37) SERPINE1TRPV1ACP1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed