SCHEMBL22993294

SCHEMBL22993294

CC(C)(C)c1ccc(-c2ccc3c(-c4cc5ccccc5c5ccccc45)c4cc(-c5ccc(OC(F)(F)F)cc5)ccc4c(-c4cc5cc(F)ccc5c5ccccc45)c3c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.37
TRPV1 Q8NER1 2/20 0.37
GPR84 Q9NQS5 1/20 0.37
DHODH Q02127 1/20 0.36
ACP1 P24666 1/20 0.35
PPARG P37231 2/20 0.34
PPARA Q07869 2/20 0.34
EPHX2 P34913 1/20 0.34
NR1H4 Q96RI1 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.34
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
KIF11 P52732 1/20 0.32
GPR3 P46089 1/20 0.32
P2RY1 P47900 1/20 0.32
TNKS O95271 1/20 0.31
PARP1 P09874 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993516 0.94 TRPV1 (0.41) SERPINE1TRPV1GPR84ACP1PPARG
SCHEMBL22993115 0.93 CYP11B1 (0.37) SERPINE1GPR84ACP1PTGDR2CYP11B1
SCHEMBL22992951 0.92 CYP11B1 (0.34) ACP1PTGDR2CYP11B1CYP11B2KIF11
SCHEMBL22993506 0.92 CYP11B1 (0.34) ACP1PTGDR2CYP11B1CYP11B2KIF11
SCHEMBL22993246 0.92 SERPINE1 (0.39) SERPINE1TRPV1GPR84ACP1PPARG
SCHEMBL22993077 0.92 SERPINE1 (0.39) SERPINE1TRPV1GPR84ACP1PPARG
SCHEMBL22993507 0.92 CYP11B1 (0.36) SERPINE1GPR84ACP1PTGDR2CYP11B1
SCHEMBL22993095 0.90 PTGDR2 (0.36) GPR84ACP1PTGDR2CYP11B1CYP11B2
SCHEMBL26803531 0.90 PTGDR2 (0.36) GPR84ACP1PTGDR2CYP11B1CYP11B2
SCHEMBL22993503 0.90 GPR84 (0.42) GPR84DHODHCYP11B1KIF11TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed