SCHEMBL22993276

SCHEMBL22993276

Fc1ccc(-c2ccc3c(-c4cccc5ccccc45)c4cc(-c5ccc(F)cc5)ccc4c(-c4cccc5ccccc45)c3c2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.42
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CA9 Q16790 3/20 0.42
MAPK13 O15264 1/20 0.42
GCGR P47871 1/20 0.42
MAPK12 P53778 1/20 0.42
MAPK11 Q15759 1/20 0.42
MAPK14 Q16539 1/20 0.42
CYP1A2 P05177 3/20 0.40
CYP1A1 P04798 2/20 0.40
CYP1B1 Q16678 2/20 0.40
XDH P47989 1/20 0.40
CYP17A1 P05093 1/20 0.40
GPR84 Q9NQS5 1/20 0.40
KDM4E B2RXH2 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22992938 0.93 CA12 (0.43) CA12CA1CA2CA9MAPK13
SCHEMBL22993277 0.93 CA12 (0.40) CA12CA1CA2CA9MAPK13
SCHEMBL15945127 0.92 MAPK13 (0.38) CA12CA1CA2CA9MAPK13
SCHEMBL15945171 0.92 MAPK13 (0.38) CA12CA1CA2CA9MAPK13
SCHEMBL22993534 0.92 DRD2 (0.38) CA12CA1CA2CA9MAPK13
SCHEMBL26803619 0.90 DRD2 (0.37) CA12CA1CA2CA9MAPK13
SCHEMBL22993316 0.90 CA12 (0.39) CA12CA1CA2CA9MAPK13
SCHEMBL22993087 0.90 TOP1 (0.42) CA12CA1CA2CA9MAPK13
SCHEMBL2955115 0.90 CA12 (0.45) CA12CA1CA2CA9CYP1A2
SCHEMBL24702941 0.89 MCL1 (0.40) CA12CA1CA2CA9MAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed