SCHEMBL22993345

SCHEMBL22993345

Fc1ccc2c(c1)cc(-c1c3ccc(-c4cc(F)c(F)c(F)c4)cc3c(-c3cc4ccccc4c4ccccc34)c3ccc(-c4ccc(OC(F)(F)F)cc4)cc13)c1ccccc12

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.34
CYP11B1 P15538 3/20 0.34
CYP11B2 P19099 3/20 0.34
ACP1 P24666 1/20 0.33
CHRM5 P08912 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
AURKA O14965 1/20 0.32
TPX2 Q9ULW0 1/20 0.32
GPR3 P46089 1/20 0.32
SCN5A Q14524 1/20 0.32
TRPA1 O75762 1/20 0.31
PPM1A P35813 1/20 0.31
SERPINE1 P05121 2/20 0.31
CCNT1 O60563 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
CDK9 P50750 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22993508 1.00 KIF11 (0.34) KIF11CYP11B1CYP11B2ACP1CHRM5
SCHEMBL22993350 0.95 KIF11 (0.38) KIF11CYP11B1CYP11B2ACP1CHRM5
SCHEMBL22993115 0.94 CYP11B1 (0.37) KIF11CYP11B1CYP11B2ACP1PTGDR2
SCHEMBL22993507 0.93 CYP11B1 (0.36) KIF11CYP11B1CYP11B2ACP1PTGDR2
SCHEMBL22993150 0.92 KIF11 (0.37) KIF11CYP11B1CYP11B2ACP1CHRM5
SCHEMBL22993280 0.89 CYP11B1 (0.38) KIF11CYP11B1CYP11B2ACP1PTGDR2
SCHEMBL26803588 0.89 KIF11 (0.34) KIF11CYP11B1CYP11B2ACP1CHRM5
SCHEMBL22993125 0.89 KIF11 (0.34) KIF11CYP11B1CYP11B2ACP1CHRM5
SCHEMBL22993506 0.89 CYP11B1 (0.34) KIF11CYP11B1CYP11B2ACP1PTGDR2
SCHEMBL22992951 0.89 CYP11B1 (0.34) KIF11CYP11B1CYP11B2ACP1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-20230363196-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS INC. (CA) 2023-11-09 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-11751415-B2 Materials for forming a nucleation-inhibiting coating and devices incorporating same OTI LUMIONICS INC. (CA) 2023-09-05 US disclosed
US-20210047536-A1 MATERIALS FOR FORMING A NUCLEATION-INHIBITING COATING AND DEVICES INCORPORATING SAME OTI LUMIONICS, INC. (CA) 2021-02-18 US disclosed