⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL27537220 | 0.95 | — | — | |
| SCHEMBL342641 | 0.94 | — | — | |
| SCHEMBL540916 | 0.85 | FDPS (0.30) | — | |
| SCHEMBL10373226 | 0.81 | — | — | |
| SCHEMBL342500 | 0.81 | FDPS (0.33) | — | |
| SCHEMBL6682775 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL771717 | 0.81 | — | — | |
| SCHEMBL1254908 | 0.81 | — | — | |
| SCHEMBL20873212 | 0.79 | FDPS (0.36) | — | |
| SCHEMBL11021919 | 0.78 | FDPS (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 793 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677466-B | Preparation method of dihydroxymethyl butyraldehyde | 宁夏百川科技有限公司 | 2025-04-11 | — | — | CN | claimed |
| CN-116874349-B | Method for preparing 2, 2-dimethylolbutyraldehyde and trimethylolpropane | 万华化学集团股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| EP-3757087-B1 | METHOD FOR MANUFACTURING DIMETHYLOLBUTANAL AND METHOD FOR MANUFACTURING TRIMETHYLOLPROPANE USING SAME | LG CHEMICAL LTD (KR) | 2023-11-15 | — | — | EP | claimed |
| CN-116874349-A | Method for preparing 2, 2-dimethylolbutyraldehyde and trimethylolpropane | 万华化学集团股份有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-116768703-A | Application of KOH in catalytic synthesis of trimethylolpropane | 武汉工程大学 | 2023-09-19 | — | — | CN | claimed |
| CN-111465590-B | Production method and distillation device of dimethylolbutyraldehyde | LG化学株式会社 | 2023-04-11 | — | — | CN | claimed |
| CN-115677466-A | Preparation method of dimethylolbutyraldehyde | 宁夏百川科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-112004791-B | Method for preparing dimethylolbutanal and method for preparing trimethylolpropane using the same | LG化学株式会社 | 2023-01-31 | — | — | CN | claimed |
| CN-112517018-B | Catalyst for preparing trimethylolpropane by hydrogenating 2, 2-dimethylolbutyraldehyde and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-08-05 | — | — | CN | claimed |
| CN-111715238-B | Hydrogenation catalyst, preparation method and application thereof | 万华化学集团股份有限公司 | 2022-08-05 | — | — | CN | claimed |
| EP-0996605-B1 | Method for the hydrogenation of carbonyl compounds | BASF AG (DE) | 2003-01-29 | — | — | EP | claimed |
| US-20020189926-A1 | Method for purifying trimethylolpropane, which is produced by hydrogenation, by means of continuous distillation | BASF AKTIENGESELLSCHAFT (DE) | 2002-12-19 | — | — | US | claimed |
| EP-1242346-A1 | METHOD FOR PURIFYING TRIMETHYLOLPROPANE, WHICH IS PRODUCED BY HYDROGENATION, BY MEANS OF CONTINUOUS DISTILLATION | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-25 | — | — | EP | claimed |
| JP-2001510172-A | — | — | 2001-07-31 | — | — | JP | claimed |
| WO-2001047847-A1 | METHOD FOR PURIFYING TRIMETHYLOLPROPANE, WHICH IS PRODUCED BY HYDROGENATION, BY MEANS OF CONTINUOUS DISTILLATION | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | WO | claimed |
| WO-2001047849-A1 | METHOD FOR THE CONVERSION OF TRIHYDROXYMETHYLALKYL FORMATE ARISING DURING PRODUCTION OF TRIHYDROXYMETHYLALKANE | BASF AKTIENGESELLSCHAFT (DE) | 2001-07-05 | — | — | WO | claimed |
| US-6207865-B1 | HYDROGENATION OF ALDEHYDES OBTAINED BY THE OXO SYNTHESIS OR THE ALDOL REACTION, RANEY COPPER CATALYST IS EMPLOYED IN THE FORM OF NUGGETS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-27 | — | — | US | claimed |
| EP-0996605-A1 | METHOD FOR THE HYDROGENATION OF CARBONYL COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-03 | — | — | EP | claimed |
| WO-1999003801-A1 | METHOD FOR THE HYDROGENATION OF CARBONYL COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-28 | — | — | WO | claimed |
| US-4313863-A | HYDROLYSIS WITH USE OF ANTISTICKING AGENTS | NITTO CHEMICAL INDUSTRY CO. LTD. (JP) | 1982-02-02 | — | — | US | claimed |