Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 8/20 | 0.37 |
| ▸ | JUN | P05412 | 3/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.37 |
| ▸ | RELA | Q04206 | 3/20 | 0.37 |
| ▸ | ATF1 | P18846 | 6/20 | 0.32 |
| ▸ | XPO1 | O14980 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2074438 | 0.73 | GAA (0.42) | — | |
| SCHEMBL16264859 | 0.70 | TYRO3 (0.34) | NFKB1JUNNFKB2RELA | |
| SCHEMBL17373087 | 0.70 | NFKB1 (0.46) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL3538817 | 0.66 | TYRO3 (0.34) | NFKB1JUNNFKB2RELA | |
| SCHEMBL23330824 | 0.66 | NFKB1 (0.42) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL23330664 | 0.65 | NFKB1 (0.38) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL17111799 | 0.65 | NFKB1 (0.40) | NFKB1JUNNFKB2RELAATF1 | |
| SCHEMBL23330662 | 0.63 | SMN1; SMN2 (0.41) | NFKB1JUNNFKB2RELA | |
| SCHEMBL1937233 | 0.63 | IDH1 (0.38) | NFKB1ATF1 | |
| SCHEMBL2071558 | 0.63 | STK17B (0.36) | NFKB1JUNNFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778584-A1 | PRODUCTION PROCESS OF 2-CHLORO-4-HETEROARYL-PYRIMIDINE DERIVATIVES | ARIAD Pharmaceuticals, Inc. (US) | 2021-02-17 | — | — | EP | disclosed |