Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128123 | 0.79 | CYP2A6 (0.43) | CYP2A6CYP1A2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4840796 | 0.78 | CYP2A6 (0.41) | CYP2A6CYP1A2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL4838237 | 0.78 | CYP2A6 (0.41) | CYP2A6CYP1A2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL2139310 | 0.76 | HPRT1 (0.50) | CYP2A6CYP1A2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL18317258 | 0.74 | HPRT1 (0.54) | CYP2A6CYP1A2ALOX12ALDH1A1TSHR | |
| SCHEMBL239122 | 0.74 | CYP2A6 (0.37) | CYP2A6CYP1A2ALOX12ALDH1A1TSHR | |
| SCHEMBL29045253 | 0.73 | CYP1A2 (0.41) | CYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL6244052 | 0.72 | — | — | |
| SCHEMBL16737102 | 0.71 | CYP1A2 (0.44) | CYP2A6CYP1A2ALDH1A1 | |
| SCHEMBL3246275 | 0.70 | NPC1 (0.37) | CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1761 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773586-B | Poly (fluorobenzene ester) polymer material and synthetic method thereof | 西安交通大学 | 2024-06-14 | — | — | CN | claimed |
| CN-117983306-A | Catalyst containing PCCP ligand for ethylene selective tetramerization and preparation method and application thereof | 华东理工大学 | 2024-05-07 | — | — | CN | claimed |
| CN-111816772-B | Perovskite solar cell, production method thereof and perovskite cell assembly | 隆基绿能科技股份有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-115594625-A | Method for preparing bazedoxifene | 济南明微医药科技有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-114773586-A | Poly (fluorophenyl ester) polymer material and synthesis method thereof | 西安交通大学 | 2022-07-22 | — | — | CN | claimed |
| CN-110225895-B | Base protective film, adhesion preventing member, and method for forming adhesion preventing member | 星和电机株式会社 | 2021-11-02 | — | — | CN | claimed |
| CN-109705648-B | Application of novel fluoronaphthalene ester film-forming assistant in color-changing coating | 上海甘田光学材料有限公司 | 2021-09-24 | — | — | CN | claimed |
| EP-3625223-B1 | PYRIMIDINE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-08-11 | — | — | EP | claimed |
| US-10829466-B2 | Stilbene derivative and preparation method thereof | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-11-10 | — | — | US | claimed |
| CN-111816772-A | Perovskite solar cell, production method and perovskite cell component | 隆基绿能科技股份有限公司 | 2020-10-23 | — | — | CN | claimed |
| US-5461074-A | Dipropargyl containing aryl/alkyl sulfur/or sulfonyl/or sulfoxide terminated aminodiol compounds are used as renin inhibitor; therpeutical | G.D. SEARLE & CO. (US) | 1995-10-24 | — | — | US | claimed |
| US-5432201-A | Alkylaminoalkyl-sulfonyl-terminated β-alanineamide amino-diol compounds for treatment of hypertension | G. D. SEARLE & CO. (US) | 1995-07-11 | — | — | US | claimed |
| US-5416119-A | Alkylaminoalkyl-terminated sulfide/sulfonyl-containing cycloalkyl-alanine amino-diol compounds for treatment of hypertension | G. D. SEARLE & CO. (US) | 1995-05-16 | — | — | US | claimed |
| US-5414018-A | Alkylaminoalkyl-terminated sulfide/sulfonyl-containing propargyl amino-diol compounds for treatment of hypertension | G. D. SEARLE & CO. (US) | 1995-05-09 | — | — | US | claimed |
| WO-1995008531-A1 | ALKYLAMINOALKYL-TERMINATED SULFIDE/SULFONYL-CONTAINING PROPARGYL AMINO-DIOL COMPOUNDS FOR TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1995-03-30 | — | — | WO | claimed |
| US-5317039-A | Renin inhibitors with peptides | G. D. SEARLE & CO. (US) | 1994-05-31 | — | — | US | claimed |
| US-5314920-A | Renin inhibitors | G. D. SEARLE & CO. (US) | 1994-05-24 | — | — | US | claimed |
| US-5312838-A | β-alanineamide aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension | G. D. SEARLE & CO. (US) | 1994-05-17 | — | — | US | claimed |
| US-5268391-A | Cardiovascular disorders | C. D. SEARLE & CO. (US) | 1993-12-07 | — | — | US | claimed |
| US-5246969-A | Oligopeptides as renin inhibitors | G. D. SEARLE & CO. (US) | 1993-09-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829466-B2 | Stilbene derivative and preparation method thereof | STS, F12, GLB1 | CYP2A6 134/4885CYP1A2 210/4885ALOX12 2824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.