Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 4/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3501089 | 0.98 | DGKA (0.52) | DGKALMNAPAMKMT2AKDM4E | |
| SCHEMBL8242353 | 0.98 | DGKA (0.52) | DGKALMNAPAMKMT2AKDM4E | |
| SCHEMBL7290690 | 0.98 | DGKA (0.52) | DGKALMNAPAMKMT2AKDM4E | |
| SCHEMBL22271695 | 0.98 | DGKA (0.52) | DGKALMNAPAMKMT2AKDM4E | |
| SCHEMBL22463686 | 0.98 | DGKA (0.52) | DGKALMNAPAMKMT2AKDM4E | |
| SCHEMBL15235923 | 0.98 | DGKA (0.52) | DGKALMNAPAMKMT2AKDM4E | |
| SCHEMBL7290205 | 0.98 | DGKA (0.52) | DGKALMNAPAMKMT2AKDM4E | |
| SCHEMBL1997072 | 0.94 | MEN1 (0.45) | DGKALMNAPAMKMT2AKDM4E | |
| SCHEMBL4953772 | 0.92 | KMT2A (0.44) | DGKALMNAKMT2AKDM4EDUSP3 | |
| SCHEMBL522462 | 0.90 | KMT2A (0.43) | DGKALMNAPAMKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105792852-B | Glucose-responsive insulin conjugates | 默沙东公司 | 2019-12-10 | — | — | CN | disclosed |
| CN-106459055-B | Difunctional cytotoxic drug agent | PFIZER INC. (US) | 2019-11-01 | — | — | CN | disclosed |
| CN-106459120-A | Substituted-6,8-dioxabicyclo[3.2.1]octane-2,3-diol compounds as targeting agents of asgpr | 辉瑞大药厂 | 2017-02-22 | — | — | CN | disclosed |
| CN-106459055-A | Bifunctional cytotoxic agents | 辉瑞大药厂 | 2017-02-22 | — | — | CN | disclosed |
| CN-105792852-A | Glucose-responsive insulin conjugates | 默沙东公司 | 2016-07-20 | — | — | CN | disclosed |
| US-7998913-B2 | Flow modifiers for improved magnetic recording device | HITACHI GLOBAL STORAGE TECHNOLOGIES NETHERLANDS B.V. (NL) | 2011-08-16 | — | — | US | disclosed |
| CN-101522610-A | Nitrate esters of amino alcohols | SPEEDEL EXPERIMENTA AG (CH) | 2009-09-02 | — | — | CN | disclosed |
| US-20080304177-A1 | FLOW MODIFIERS FOR IMPROVED MAGNETIC RECORDING DEVICE | WESTERN DIGITAL TECHNOLOGIES, INC. | 2008-12-11 | — | — | US | disclosed |
| CN-1298299-A | Antibacterial agent | BRITISH BIOTECH PHARM (GB) | 2001-06-06 | — | — | CN | disclosed |
| EP-0742790-A4 | SUBSTITUTED PURINES AND OLIGONUCLEOTIDE CROSS-LINKING | ISIS PHARMACEUTICALS INC (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0742790-A1 | SUBSTITUTED PURINES AND OLIGONUCLEOTIDE CROSS-LINKING | ISIS PHARMACEUTICALS, INC. (US) | 1996-11-20 | — | — | EP | disclosed |
| WO-1995021184-A1 | SUBSTITUTED PURINES AND OLIGONUCLEOTIDE CROSS-LINKING | ISIS PHARMACEUTICALS, INC. (US) | 1995-08-10 | — | — | WO | disclosed |