SCHEMBL2299565

SCHEMBL2299565

O=C(O)C(CCCCCCCCCCCCCCc1ccccc1)[N+](=O)[O-]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.49
MAPT P10636 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
TRPV1 Q8NER1 2/20 0.45
S1PR2 O95136 1/20 0.44
S1PR4 O95977 1/20 0.44
S1PR1 P21453 1/20 0.44
S1PR3 Q99500 1/20 0.44
HDAC1 Q13547 4/20 0.44
HDAC2 Q92769 3/20 0.44
ALOX5 P09917 1/20 0.44
HDAC3 O15379 2/20 0.44
HDAC4 P56524 2/20 0.44
HDAC7 Q8WUI4 2/20 0.44
HDAC10 Q969S8 2/20 0.44
HDAC11 Q96DB2 2/20 0.44
HDAC8 Q9BY41 2/20 0.44
HDAC6 Q9UBN7 2/20 0.44
HDAC9 Q9UKV0 2/20 0.44
HDAC5 Q9UQL6 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3847839 1.00 TRPA1 (0.49) TRPA1MAPTRXFP1TRPV1S1PR2
SCHEMBL3660415 1.00 TRPA1 (0.49) TRPA1MAPTRXFP1TRPV1S1PR2
SCHEMBL3663770 1.00 TRPA1 (0.49) TRPA1MAPTRXFP1TRPV1S1PR2
SCHEMBL6248797 1.00 TRPA1 (0.49) TRPA1MAPTRXFP1TRPV1S1PR2
SCHEMBL3969389 0.98 TRPA1 (0.47) TRPA1MAPTRXFP1TRPV1HDAC1
SCHEMBL4726273 0.94 GRIK1 (0.49) MAPTRXFP1HDAC1HDAC2HDAC3
SCHEMBL475203 0.87 CPA1 (0.47) CPA1
SCHEMBL12813142 0.84 MAPT (0.47) TRPA1MAPTRXFP1S1PR2S1PR1
SCHEMBL12813233 0.84 MAPT (0.47) TRPA1MAPTRXFP1S1PR2S1PR1
SCHEMBL12813363 0.82 MAPT (0.48) TRPA1MAPTRXFP1S1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114306511-B Compound composition and application thereof in preparing medicine for preventing and treating skin diseases caused by malassezia bacteria 宁夏职业技术学院(宁夏广播电视大学) 2023-03-14 CN disclosed
CN-114306511-A Compound composition and application thereof in preparing medicine for preventing and treating skin diseases caused by malassezia bacteria 宁夏职业技术学院(宁夏广播电视大学) 2022-04-12 CN disclosed
WO-2020045971-A1 HUMAN-DERIVED LACTOBACILLUS FERMENTUM MG4231 OR LACTOBACILLUS FERMENTUM MG4244 STRAIN HAVING ANTI-OBESITY ACTIVITY, AND COMPOSITION COMPRISING SAME 주식회사 메디오젠 2020-03-05 WO disclosed
WO-2020045972-A1 HUMAN BODY-DERIVED LACTOBACILLUS FERMENTUM MG4231 OR LACTOBACILLUS FERMENTUM MG4244 STRAIN HAVING ANTI-OBESITY ACTIVITY AND COMPOSITION COMPRISING SAME 주식회사 메디오젠 2020-03-05 WO disclosed
EP-3274458-A1 SENSORS FOR DETECTION AND QUANTIFICATION OF MICROBIOLOGICAL PROTEIN SECRETION SenseUp GmbH (DE) 2018-01-31 EP disclosed
WO-2016151054-A1 SENSORS FOR DETECTION AND QUANTIFICATION OF MICROBIOLOGICAL PROTEIN SECRETION Forschungszentrum Jülich GmbH (DE) 2016-09-29 WO disclosed
WO-2015018884-A1 WASHING OR CLEANING COMPOSITION COMPRISING IMMOBILIZED ENZYME COMPONENT HENKEL AG & CO. KGAA (DE) 2015-02-12 WO disclosed
WO-2014183744-A2 ANHYDROUS IMMOBILIZATION OF ENZYMES BRANDENBURGISCHE TECHNISCHE UNIVERSITÄT COTTBUS-SENFTENBERG (DE) 2014-11-20 WO disclosed
US-20130184449-A1 DNA Encoding a Plant Lipase, Transgenic Plants and a Method for Controlling Senescence in Plants THOMPSON JOHN E (CA) 2013-07-18 US disclosed
EP-2576795-A1 A METHOD FOR PRODUCING A POLYPEPTIDE IN YARROWIA LIPOLYTICA CSIR (ZA) 2013-04-10 EP disclosed
EP-1896577-A2 LIPASES FOR PHARMACEUTICAL USE Novozymes A/S (DK) 2008-03-12 EP disclosed
US-20070011778-A1 DNA encoding a plant lipase, transgenic plants and a method for controlling senescence in plants SENESCO TECHNOLOGIES, INC. (US) 2007-01-11 US disclosed
WO-2006136159-A2 LIPASES FOR PHARMACEUTICAL USE NOVOZYMES A/S (DK) 2006-12-28 WO disclosed
EP-1709169-A1 STABILIZATION OF ENZYMES CSIR (ZA) 2006-10-11 EP disclosed
WO-2005080561-A1 STABILIZATION OF ENZYMES CSIR (ZA) 2005-09-01 WO disclosed
EP-1294916-A2 DNA ENCODING A PLANT LIPASE, TRANSGENIC PLANTS AND A METHOD FOR CONTROLLING SENESCENCE IN PLANTS Senesco Technologies, Inc. (US) 2003-03-26 EP disclosed
WO-2000049164-A9 DNA ENCODING A PLANT LIPASE, TRANSGENIC PLANTS AND A METHOD FOR CONTROLLING SENESCENCE IN PLANTS SENESCO INC (US) 2002-04-11 WO disclosed
WO-2001098510-A2 DNA ENCODING A PLANT LIPASE, TRANSGENIC PLANTS AND A METHOD FOR CONTROLLING SENESCENCE IN PLANTS SENESCO TECHNOLOGIES, INC. (US) 2001-12-27 WO disclosed
EP-1155134-A1 DNA ENCODING A PLANT LIPASE, TRANSGENIC PLANTS AND A METHOD FOR CONTROLLING SENESCENCE IN PLANTS Senesco, Inc. (US) 2001-11-21 EP disclosed
WO-2000049164-A1 DNA ENCODING A PLANT LIPASE, TRANSGENIC PLANTS AND A METHOD FOR CONTROLLING SENESCENCE IN PLANTS SENESCO, INC. (US) 2000-08-24 WO disclosed