Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20009636 | 0.87 | KMT2A (0.39) | KMT2APOLBL3MBTL1TAS1R3TAS1R1 | |
| SCHEMBL17747010 | 0.82 | KMT2A (0.44) | KMT2APOLB | |
| SCHEMBL17747023 | 0.82 | KMT2A (0.44) | KMT2APOLB | |
| SCHEMBL17746958 | 0.82 | NOD1 (0.48) | KMT2APOLB | |
| SCHEMBL17746954 | 0.82 | NOD1 (0.48) | KMT2APOLB | |
| SCHEMBL20009571 | 0.80 | HDAC8 (0.35) | KMT2APOLBL3MBTL1HDAC2 | |
| SCHEMBL17746994 | 0.77 | HDAC8 (0.43) | KMT2APOLB | |
| SCHEMBL17747018 | 0.77 | HDAC8 (0.43) | KMT2APOLB | |
| SCHEMBL17747020 | 0.77 | HDAC8 (0.43) | KMT2APOLB | |
| SCHEMBL17746996 | 0.77 | HDAC8 (0.43) | KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778622-A1 | MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2021-02-17 | — | — | EP | disclosed |