Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22996203 | 0.79 | PTGDR2 (0.33) | RETMEN1ALDH1A1KMT2AATM | |
| SCHEMBL3155322 | 0.78 | RET (0.41) | RETMEN1ALDH1A1KMT2AATM | |
| SCHEMBL3167531 | 0.78 | PTGDR2 (0.32) | RETMEN1ALDH1A1KMT2AATM | |
| SCHEMBL8254522 | 0.77 | LMNA (0.43) | MEN1ALDH1A1KMT2AATMLMNA | |
| SCHEMBL21908096 | 0.76 | BRD4 (0.34) | RETMEN1ALDH1A1KMT2AATM | |
| SCHEMBL28791949 | 0.75 | PTGDR2 (0.31) | RETMEN1ALDH1A1KMT2AATM | |
| SCHEMBL21191135 | 0.75 | RET (0.40) | RETMEN1ALDH1A1KMT2AATM | |
| SCHEMBL18949094 | 0.73 | GAA (0.32) | MEN1ALDH1A1KMT2AATMLMNA | |
| SCHEMBL16019485 | 0.72 | RET (0.32) | RET | |
| SCHEMBL23114349 | 0.70 | NR1H4 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010076-B1 | (HETERO)ARYL-METHYL-THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2024-01-17 | — | — | EP | disclosed |
| WO-2021028336-A1 | (HETERO)ARYL-METHYL-THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2021-02-18 | — | — | WO | disclosed |