Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16922688 | 0.91 | KDM4E (0.55) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14379370 | 0.87 | KDM4E (0.58) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12781877 | 0.79 | MAPT (0.58) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1911899 | 0.79 | MAPT (0.53) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22996827 | 0.78 | ALDH1A1 (0.50) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL25796640 | 0.77 | MAPT (0.49) | KDM4EMAPTALDH1A1HTTLMNA | |
| SCHEMBL17384715 | 0.77 | ALDH1A1 (0.42) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7534270 | 0.76 | KDM4E (0.55) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL2436520 | 0.76 | KDM4E (0.55) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28991680 | 0.76 | KDM4E (0.46) | KDM4EMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021030438-A1 | COMPOUNDS FOR INHIBITION OF ALPHA 4 BETA 7 INTEGRIN | GILEAD SCIENCES, INC. (US) | 2021-02-18 | — | — | WO | disclosed |