Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 18/20 | 0.61 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298115 | 0.90 | FASN (0.61) | FASN | |
| SCHEMBL2298123 | 0.90 | FASN (0.61) | FASN | |
| SCHEMBL2357729 | 0.90 | FASN (0.57) | FASNALOX5APFEN1 | |
| SCHEMBL14227287 | 0.90 | FASN (0.64) | FASN | |
| SCHEMBL14151542 | 0.89 | FASN (0.65) | FASN | |
| SCHEMBL2297950 | 0.88 | FASN (0.64) | FASN | |
| SCHEMBL2297960 | 0.88 | FASN (0.64) | FASN | |
| SCHEMBL2364660 | 0.87 | FASN (0.61) | FASN | |
| SCHEMBL2357351 | 0.87 | FASN (0.61) | FASN | |
| SCHEMBL2357353 | 0.87 | FASN (0.61) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103546-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-08-25 | — | — | WO | disclosed |