Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 18/20 | 0.57 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12426814 | 0.90 | FASN (0.59) | FASN | |
| SCHEMBL14151834 | 0.90 | FASN (0.59) | FASN | |
| SCHEMBL2299747 | 0.90 | FASN (0.61) | FASNALOX5APFEN1 | |
| SCHEMBL2297993 | 0.89 | FASN (0.61) | FASN | |
| SCHEMBL2298006 | 0.89 | FASN (0.61) | FASN | |
| SCHEMBL14152399 | 0.88 | FASN (0.60) | FASN | |
| SCHEMBL2301429 | 0.87 | FASN (0.62) | FASN | |
| SCHEMBL2301422 | 0.87 | FASN (0.62) | FASN | |
| SCHEMBL2301018 | 0.87 | FASN (0.59) | FASN | |
| SCHEMBL2357685 | 0.87 | FASN (0.59) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858175-A | Triazolones as fatty acid synthase inhibitors | GLAXOSMITHKLINE LLC | 2013-01-02 | — | — | CN | disclosed |
| WO-2011103546-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-08-25 | — | — | WO | disclosed |