Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 6/20 | 0.66 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.66 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.66 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.66 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.59 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7125340 | 0.89 | LPAR3 (0.75) | S1PR2S1PR1S1PR3S1PR5LPAR3 | |
| Trolamine SCHEMBL9576536 | 0.85 | LPAR3 (0.69) | S1PR2S1PR1S1PR3S1PR5LPAR3 | |
| SCHEMBL29774223 | 0.85 | S1PR2 (0.62) | S1PR2S1PR1S1PR3S1PR5LPAR3 | |
| Docosanol SCHEMBL31540309 | 0.85 | LPAR3 (0.82) | S1PR2S1PR1S1PR3S1PR5LPAR3 | |
| Bromide SCHEMBL17394576 | 0.83 | LPAR3 (0.72) | S1PR2S1PR1S1PR3S1PR5LPAR3 | |
| SCHEMBL4937294 | 0.82 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL1404090 | 0.82 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Octanol SCHEMBL22656886 | 0.82 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL1404085 | 0.82 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Octanol SCHEMBL11125952 | 0.82 | LMNA (0.68) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |