Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.56 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.56 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.44 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.44 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23001236 | 1.00 | LPAR3 (0.56) | LPAR3LPAR2LPAR1LPAR5PLA2G2D | |
| SCHEMBL17887101 | 0.86 | LPAR3 (0.60) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL7184210 | 0.83 | LPAR3 (0.56) | LPAR3LPAR2LPAR1LPAR5PLA2G2D | |
| SCHEMBL7107080 | 0.83 | LPAR3 (0.56) | LPAR3LPAR2LPAR1LPAR5PLA2G2D | |
| SCHEMBL17887099 | 0.82 | LPAR3 (0.64) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL29194068 | 0.82 | LPAR3 (0.64) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL18708275 | 0.82 | LPAR3 (0.64) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL7804496 | 0.81 | LPAR3 (0.53) | LPAR3LPAR2LPAR1SMPD1FDPS | |
| SCHEMBL28849493 | 0.80 | LPAR3 (0.61) | LPAR3LPAR2LPAR1LPAR5FDPS | |
| SCHEMBL17626432 | 0.78 | LPAR3 (0.59) | LPAR3LPAR2LPAR1LPAR5FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |