Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.56 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.56 |
| ▸ | LPAR1 | Q92633 | 5/20 | 0.56 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | LAP3 | P28838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7184210 | 1.00 | LPAR3 (0.56) | LPAR3LPAR2LPAR1LPAR5HTT | |
| SCHEMBL7551578 | 0.91 | LPAR3 (0.59) | LPAR3LPAR2LPAR1 | |
| SCHEMBL15323486 | 0.84 | LPAR3 (0.53) | LPAR3LPAR2LPAR1LPAR5HTT | |
| SCHEMBL23001236 | 0.83 | LPAR3 (0.56) | LPAR3LPAR2LPAR1LPAR5HTT | |
| SCHEMBL23001237 | 0.83 | LPAR3 (0.56) | LPAR3LPAR2LPAR1LPAR5HTT | |
| SCHEMBL11884531 | 0.79 | LPAR1 (0.66) | LPAR3LPAR2LPAR1LPAR5HTT | |
| SCHEMBL11111004 | 0.79 | LPAR3 (0.60) | LPAR3LPAR2LPAR1LPAR5FDPS | |
| SCHEMBL17887099 | 0.78 | LPAR3 (0.64) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL18708275 | 0.78 | LPAR3 (0.64) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL29194068 | 0.78 | LPAR3 (0.64) | LPAR3LPAR2LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083313-A1 | Treatment of breast cancer with a liposome mixture comprising an antineoplastic alkylphospholipid and water- or lipid-soluble antiestrogen agents | MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2003-05-01 | — | — | US | claimed |
| EP-1135193-B1 | AGENTS PROVIDED FOR TREATING TUMORS, BASED ON LIPOSOMES, AND CONTAINING TAMOXIFEN | MAX DELBRUECK CENTRUM (DE) | 2002-10-30 | — | — | EP | claimed |
| US-20030083313-A1 | Treatment of breast cancer with a liposome mixture comprising an antineoplastic alkylphospholipid and water- or lipid-soluble antiestrogen agents | MAX-DELBRUCK-CENTRUM FUR MOLEKULARE MEDIZIN (DE) | 2003-05-01 | — | — | US | disclosed |