Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 3/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | PPIA | P62937 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21452505 | 0.89 | GRIN1 (0.38) | BDKRB1GRIN1GRIN2AGRIN2BSLC6A4 | |
| SCHEMBL21452562 | 0.85 | KCNQ3 (0.37) | GRIN1GRIN2AGRIN2BPPIASLC6A4 | |
| SCHEMBL21451917 | 0.83 | GRIN1 (0.40) | BDKRB1GRIN1GRIN2AGRIN2BSLC6A4 | |
| SCHEMBL23002199 | 0.83 | BDKRB1 (0.34) | BDKRB1OPRK1LMNA | |
| SCHEMBL21452415 | 0.81 | HDAC4 (0.47) | GRIN1GRIN2AHDAC4GRIN2BSLC6A4 | |
| SCHEMBL31426693 | 0.81 | HDAC4 (0.47) | GRIN1GRIN2AHDAC4GRIN2BSLC6A4 | |
| SCHEMBL21451950 | 0.81 | HDAC4 (0.39) | BDKRB1GRIN1GRIN2AHDAC4GRIN2B | |
| SCHEMBL21451939 | 0.81 | HDAC4 (0.36) | BDKRB1GRIN1GRIN2AHDAC4GRIN2B | |
| SCHEMBL21451902 | 0.80 | HDAC4 (0.40) | BDKRB1GRIN1GRIN2AHDAC4GRIN2B | |
| SCHEMBL21452370 | 0.80 | HDAC4 (0.47) | GRIN1GRIN2AHDAC4GRIN2BPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778579-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jianhe Pharmaceutical & Technology Co. Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |