Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21452558 | 0.90 | PSEN1 (0.35) | BDKRB1PSEN1APPHTR1AADRA2A | |
| SCHEMBL21451923 | 0.86 | FFAR4 (0.36) | FFAR4TMEM97SIGMAR1BRAF | |
| SCHEMBL21451915 | 0.85 | BDKRB1 (0.36) | BDKRB1PSEN1APPHTR1AADRA2A | |
| SCHEMBL23002201 | 0.83 | BDKRB1 (0.35) | BDKRB1LMNAOPRK1 | |
| SCHEMBL23490927 | 0.83 | PSEN1 (0.35) | LMNANPSR1DDB1CRBNRORC | |
| SCHEMBL21452175 | 0.82 | HDAC4 (0.39) | BDKRB1DDB1CRBNRORCCYP3A4 | |
| SCHEMBL21451948 | 0.82 | RIPK1 (0.33) | BDKRB1DDB1CRBNDPP8DPP9 | |
| SCHEMBL21452516 | 0.82 | DDB1 (0.35) | BDKRB1DDB1CRBNDPP8DPP9 | |
| SCHEMBL21451903 | 0.82 | DDB1 (0.36) | BDKRB1DDB1CRBNRORCPSEN1 | |
| SCHEMBL23490930 | 0.82 | DDB1 (0.35) | BDKRB1DDB1CRBNDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778579-A1 | AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jianhe Pharmaceutical & Technology Co. Ltd. (CN) | 2021-02-17 | — | — | EP | disclosed |