Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300286 | 1.00 | USP2 (0.33) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL12426626 | 0.83 | ALDH1A1 (0.34) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL12426633 | 0.83 | ALDH1A1 (0.34) | USP2ALDH1A1LMNACYP1A2TSHR | |
| Gabapentin Enacarbil SCHEMBL25455 | 0.81 | ALDH1A1 (0.41) | USP2ALDH1A1LMNACYP1A2TSHR | |
| Gabapentin Enacarbil SCHEMBL977603 | 0.81 | ALDH1A1 (0.41) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL24850 | 0.79 | ALDH1A1 (0.41) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL25397 | 0.78 | ALDH1A1 (0.40) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL2300278 | 0.78 | USP2 (0.30) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL828564 | 0.77 | ALDH1A1 (0.39) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL824843 | 0.77 | ALDH1A1 (0.39) | USP2ALDH1A1LMNACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101245-A1 | NITRIC OXIDE RELEASING COMPOUNDS FOR THE TREATMENT OF NEUROPATHIC PAIN | NICOX S.A. (FR) | 2011-08-25 | — | — | WO | disclosed |