Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28166486 | 0.98 | L3MBTL1 (0.49) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL21005661 | 0.98 | L3MBTL1 (0.49) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL18638771 | 0.98 | L3MBTL1 (0.49) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL2209793 | 0.97 | L3MBTL1 (0.47) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL29252417 | 0.97 | L3MBTL1 (0.47) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| Fluoride SCHEMBL29252822 | 0.97 | L3MBTL1 (0.47) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL18737228 | 0.97 | L3MBTL1 (0.50) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| Hydrochloric Acid SCHEMBL2207480 | 0.95 | L3MBTL1 (0.49) | L3MBTL1TDP1TBXAS1LMNAPOLB | |
| SCHEMBL15417856 | 0.92 | L3MBTL1 (0.47) | L3MBTL1TDP1TBXAS1LMNASMN1; SMN2 | |
| SCHEMBL24016025 | 0.92 | L3MBTL1 (0.47) | L3MBTL1TDP1TBXAS1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11623971-B2 | Freestanding ion gel and method for preparing the same | Research & Business Foundation Sungkyunkwan University (KR) | 2023-04-11 | — | — | US | disclosed |
| US-20210054127-A1 | FREESTANDING ION GEL AND METHOD FOR PREPARING THE SAME | Research & Business Foundation Sungkyunkwan University (KR) | 2021-02-25 | — | — | US | disclosed |