Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LDLR | P01130 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23005715 | 0.87 | AAK1 (0.43) | AAK1IDO1CHEK2HSD17B10SCN10A | |
| SCHEMBL23005583 | 0.81 | AAK1 (0.57) | AAK1IDO1SCN10ACYP2D6CYP2C9 | |
| SCHEMBL23005801 | 0.79 | HSD17B10 (0.51) | AAK1IDO1CHEK2HSD17B10GRIN2B | |
| SCHEMBL23005681 | 0.78 | AAK1 (0.47) | AAK1IDO1CHEK2HSD17B10GRIN2B | |
| SCHEMBL23005798 | 0.76 | HSD17B10 (0.36) | HSD17B10F2SCN10AMAPTF10 | |
| SCHEMBL23005627 | 0.76 | IDO1 (0.38) | AAK1IDO1HSD17B10SCN10AGRIN2B | |
| SCHEMBL23005682 | 0.76 | AAK1 (0.47) | AAK1IDO1CHEK2SCN10AGRIN2B | |
| SCHEMBL23005709 | 0.76 | AAK1 (0.45) | AAK1IDO1CHEK2HSD17B10F2 | |
| SCHEMBL23005558 | 0.73 | AAK1 (0.43) | AAK1IDO1CHEK2F2CYP2D6 | |
| SCHEMBL13435561 | 0.73 | AAK1 (0.63) | AAK1IDO1GRIN2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027724-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2021-02-18 | — | — | WO | disclosed |