Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23005566 | 0.87 | HSD17B10 (0.47) | HSD17B10AAK1CHEK2MAPTGRIN2B | |
| SCHEMBL23005703 | 0.81 | AAK1 (0.59) | AAK1CHEK2GRIN2BGRIN1NPC1 | |
| SCHEMBL23005681 | 0.80 | AAK1 (0.47) | HSD17B10AAK1CHEK2MAPTGRIN2B | |
| SCHEMBL23005553 | 0.79 | AAK1 (0.47) | HSD17B10AAK1CHEK2MAPTGRIN2B | |
| SCHEMBL23005709 | 0.77 | AAK1 (0.45) | HSD17B10AAK1CHEK2MAPTGRIN2B | |
| SCHEMBL11190008 | 0.76 | L3MBTL1 (0.47) | MAPTNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL23005715 | 0.75 | AAK1 (0.43) | HSD17B10AAK1CHEK2MAPTGRIN2B | |
| SCHEMBL23005558 | 0.75 | AAK1 (0.43) | AAK1CHEK2IDO1CYP2D6CYP2C9 | |
| SCHEMBL13435561 | 0.74 | AAK1 (0.63) | AAK1MAPTGRIN2BGRIN1NPC1 | |
| SCHEMBL23005638 | 0.74 | AAK1 (0.42) | HSD17B10AAK1CHEK2MAPTGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027724-A1 | IMMUNOMODULATOR | 成都先导药物开发股份有限公司 | 2021-02-18 | — | — | WO | disclosed |