Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 19/20 | 0.43 |
| ▸ | TGFBR2 | P37173 | 6/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29363331 | 0.81 | TGFBR1 (0.43) | TGFBR1TGFBR2MAPK14CYP2A6 | |
| SCHEMBL23007689 | 0.81 | TGFBR1 (0.43) | TGFBR1TGFBR2MAPK14CYP2A6 | |
| SCHEMBL29366479 | 0.80 | TGFBR1 (0.45) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL23007881 | 0.80 | TGFBR1 (0.45) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL23007685 | 0.78 | TGFBR1 (0.43) | TGFBR1TGFBR2MAPK14CYP2A6CYP3A4 | |
| SCHEMBL29365637 | 0.77 | TGFBR1 (0.44) | TGFBR1TGFBR2MAPK14CYP2A6 | |
| SCHEMBL23007894 | 0.77 | TGFBR1 (0.44) | TGFBR1TGFBR2MAPK14CYP2A6 | |
| SCHEMBL23007681 | 0.73 | TGFBR1 (0.35) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL23008010 | 0.72 | TGFBR1 (0.38) | TGFBR1TGFBR2MAPK14 | |
| SCHEMBL23007702 | 0.72 | TGFBR1 (0.35) | TGFBR1TGFBR2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021027594-A1 | IMIDAZOLOPYRIMIDINE COMPOUNDS COMPRISING FUSED RING GROUP, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2021-02-18 | — | — | WO | disclosed |