⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261253 | 0.70 | MAOA (0.35) | — | |
| SCHEMBL157615 | 0.67 | CA12 (0.47) | — | |
| SCHEMBL126263 | 0.67 | — | — | |
| SCHEMBL451134 | 0.65 | — | — | |
| SCHEMBL449907 | 0.65 | — | — | |
| SCHEMBL452632 | 0.65 | — | — | |
| SCHEMBL8394661 | 0.65 | — | — | |
| SCHEMBL19582841 | 0.64 | — | — | |
| SCHEMBL130886 | 0.64 | — | — | |
| SCHEMBL21295793 | 0.63 | PTPN1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6325 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145659-A1 | HETEROCYCLE FUSED GAMMA-CARBOLINES ACTING ON THE SEROTONINE 5-HT2A RECEPTOR | INTRA-CELLULAR THERAPIES, INC. (US) | 2024-07-04 | — | — | WO | claimed |
| US-11827616-B2 | Heterocyclic compounds as pesticides | DISCOVERY PURCHASER CORPORATION (US) | 2023-11-28 | — | — | US | claimed |
| US-20230339904-A1 | ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS | BIOTHERYX, INC. | 2023-10-26 | — | — | US | claimed |
| CN-116802179-A | BCL-2 inhibitors | 百济神州有限公司 | 2023-09-22 | — | — | CN | claimed |
| US-20230159522-A1 | BCL-2 INHIBITOR | BEONE MEDICINES I GMBH (CH) | 2023-05-25 | — | — | US | claimed |
| US-20230148194-A1 | SUBSTITUTED AMINOQUINOLONES AS DGKALPHA INHIBITORS FOR IMMUNE ACTIVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-11 | — | — | US | claimed |
| EP-4136084-A1 | BCL-2 INHIBITOR | BeiGene, Ltd. (KY) | 2023-02-22 | — | — | EP | claimed |
| US-20220298135-A1 | 5-HETEROARYL-PYRIDIN-2-AMINE COMPOUNDS AS NEUROPEPTIDE FF RECEPTOR ANTAGONISTS | DOMAIN THERAPEUTICS (FR) | 2022-09-22 | — | — | US | claimed |
| CN-115003665-A | Substituted aminoquinolones as immunoactive DGK alpha inhibitors | 拜耳公司 | 2022-09-02 | — | — | CN | claimed |
| US-RE49118-E1 | Material for organic electroluminescence device and electroluminescence device employing the same | IDEMITSU KOSAN CO., LTD. (JP) | 2022-06-28 | — | — | US | claimed |
| US-5336676-A | [3H,7H]thiazolo[3,4-a]pyridines with antiasthmatic and antiinflammatory actions on the respiratory tract | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-08-09 | — | — | US | claimed |
| WO-1994016361-A1 | THERMAL IMAGING MATERIAL AND PREPARATION | LABELON CORPORATION (US) | 1994-07-21 | — | — | WO | claimed |
| EP-0572449-A1 | (AMIDOMETHYL)NITROGEN HETEROCYCLIC ANALGESICS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-12-08 | — | — | EP | claimed |
| US-5254663-A | Using phthalazone as intermediate; high glass transition temperature | HAY ALLAN S (CA) | 1993-10-19 | — | — | US | claimed |
| US-5237062-A | Polymers derived from phenolphthaleins | HAY ALLAN S (CA) | 1993-08-17 | — | — | US | claimed |
| WO-1993011134-A1 | [3H,7H]THIAZOLE[3,4-a]PYRIDINES HAVING ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIVITIES ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-06-10 | — | — | WO | claimed |
| WO-1992012128-A1 | (AMIDOMETHYL)NITROGEN HETEROCYCLIC ANALGESICS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-07-23 | — | — | WO | claimed |
| EP-0361204-A2 | Optical recording materials, method for preparing the same and optical cards having the same | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-04-04 | — | — | EP | claimed |
| CN-87100354-A | Derivatives of 7- (azabicycloalkyl) -quinolone-and 7- (azabicycloalkyl) -naphthyridonecarboxylic acids | — | 1987-09-02 | — | — | CN | claimed |
| US-4213784-A | Process for producing heat developable light-sensitive compositions and elements | FUJI PHOTO FILM CO., LTD. (JP) | 1980-07-22 | — | — | US | claimed |