SCHEMBL23008702

SCHEMBL23008702

Brc1ccc(N(c2ccccc2)c2ccc(-c3cc4ccccc4c4ccccc34)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 1/20 0.43
CYP11B1 P15538 1/20 0.41
ALDH1A1 P00352 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 3/20 0.40
MAPT P10636 2/20 0.40
HPGD P15428 2/20 0.40
MPI P34949 1/20 0.40
GPR84 Q9NQS5 3/20 0.39
MAPK1 P28482 2/20 0.38
RXFP1 Q9HBX9 2/20 0.38
NISCH Q9Y2I1 1/20 0.36
ADORA3 P0DMS8 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29153947 0.97 CYP11B1 (0.42) GRM2CYP11B1ALDH1A1MEN1KMT2A
SCHEMBL29407149 0.95 ALDH1A1 (0.46) GRM2CYP11B1ALDH1A1MEN1KMT2A
SCHEMBL13897346 0.92 CYP11B1 (0.46) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL22671108 0.92 CYP11B1 (0.46) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL30701795 0.92 CYP11B1 (0.46) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL17740603 0.91 GRM2 (0.41) GRM2CYP11B1ALDH1A1MEN1KMT2A
SCHEMBL22108198 0.90 CYP11B1 (0.45) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL21796046 0.90 CYP11B1 (0.45) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL9889179 0.90 CYP11B1 (0.45) CYP11B1ALDH1A1MEN1KMT2AKDM4E
SCHEMBL9888971 0.90 CYP11B1 (0.45) CYP11B1ALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021029709-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2021-02-18 WO disclosed