⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18960 | 0.96 | — | — | |
| SCHEMBL656963 | 0.96 | CHRNA7 (0.33) | — | |
| SCHEMBL9349701 | 0.92 | CHRNA7 (0.32) | — | |
| Iodide SCHEMBL3277614 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL2962579 | 0.92 | CHRNA7 (0.32) | — | |
| SCHEMBL538360 | 0.92 | — | — | |
| Fluoride SCHEMBL2112417 | 0.92 | CHRNA7 (0.32) | — | |
| Water SCHEMBL1542414 | 0.92 | CHRNA7 (0.32) | — | |
| Hydrochloric Acid SCHEMBL353996 | 0.92 | — | — | |
| Water SCHEMBL5409123 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838534-B2 | Quinuclidine derivatives as M3 antagonists | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-11-23 | — | — | US | claimed |
| EP-2049533-A2 | QUINUCLIDINE DERIVATIVES AS M3 ANTAGONISTS | CHIESI FARMACEUTICI S.p.A. (IT) | 2009-04-22 | — | — | EP | claimed |
| US-20080039493-A1 | Quinuclidine derivatives as M3 antagonists | CHIESI FARMACEUTICI S.P.A. | 2008-02-14 | — | — | US | claimed |
| WO-2008012290-A2 | QUINUCLIDINE DERIVATIVES AS M3 ANTAGONISTS | CHIESI FARMACEUTICI S.P.A. (IT) | 2008-01-31 | — | — | WO | claimed |
| EP-1882691-A1 | Quinuclidine derivatives as M3 antagonists | CHIESI FARMACEUTICI S.p.A. (IT) | 2008-01-30 | — | — | EP | claimed |
| US-20230118142-A1 | AGENTS FOR USE IN THE TREATMENT OF TISSUE DAMAGE | UCL BUSINESS LTD (GB) | 2023-04-20 | — | — | US | disclosed |
| EP-4106754-A1 | AGENTS FOR USE IN THE TREATMENT OF TISSUE DAMAGE | UCL Business PLC (GB) | 2022-12-28 | — | — | EP | disclosed |
| EP-3383867-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2021-04-14 | — | — | EP | disclosed |
| EP-3383867-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.A. (IT) | 2018-10-10 | — | — | EP | disclosed |
| US-9932338-B2 | Compounds having muscarinic receptor antagonist and BETA2 adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-04-03 | — | — | US | disclosed |
| WO-2017093208-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-06-08 | — | — | WO | disclosed |
| US-20170158694-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2017-06-08 | — | — | US | disclosed |
| US-7838534-B2 | Quinuclidine derivatives as M3 antagonists | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-11-23 | — | — | US | disclosed |
| EP-2154136-A1 | Quinuclidine carbonate derivatives and medicinal compositions thereof | CHIESI FARMACEUTICI S.p.A. (IT) | 2010-02-17 | — | — | EP | disclosed |
| WO-2010015324-A1 | QUINUCLIDINE CARBONATE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-02-11 | — | — | WO | disclosed |
| US-20100035922-A1 | QUINUCLIDINE CARBONATE SALTS AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMACEUTICI S.P.A. (IT) | 2010-02-11 | — | — | US | disclosed |
| EP-2049533-A2 | QUINUCLIDINE DERIVATIVES AS M3 ANTAGONISTS | CHIESI FARMACEUTICI S.p.A. (IT) | 2009-04-22 | — | — | EP | disclosed |
| US-20080039493-A1 | Quinuclidine derivatives as M3 antagonists | CHIESI FARMACEUTICI S.P.A. | 2008-02-14 | — | — | US | disclosed |
| WO-2008012290-A2 | QUINUCLIDINE DERIVATIVES AS M3 ANTAGONISTS | CHIESI FARMACEUTICI S.P.A. (IT) | 2008-01-31 | — | — | WO | disclosed |
| EP-1882691-A1 | Quinuclidine derivatives as M3 antagonists | CHIESI FARMACEUTICI S.p.A. (IT) | 2008-01-30 | — | — | EP | disclosed |